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The History of Hormone Replacement Therapy

The use of hormone replacement therapy dates back to the 1940s. Women experiencing menopause wanted something to help them cope with the sometimes, debilitating side effects of the change. Menopause is the natural process every woman's body experiences when the menstrual cycle stops. The hormones produced by the ovaries help regulate a woman's body and without those hormones, women experience night sweats, sexual disorders, hot flashes, mood swings and insomnia. Hormone replacement therapy puts those hormones back into the body so a woman can function.

Although synthetic hormones were given to some women in the 40s, it did not become a widely accepted practice until well into the 1960s. It was then that pharmaceutical companies began experimenting and distributing the replacement hormones. During that time, advertisement campaigns began showing menopause as a disease and that drugs were needed to cure the disease. Women, who at the time were working more out of the home, needed to find ways to more effectively deal with the unpleasant side effects associated with menopause. This drove the demand for hormone replacement therapy up and doctors began prescribing the therapy.

As the ability to incorporate the newest technology into prescription drugs, pharmaceutical companies began producing more. Until the late 70s, hormone replacement drugs were widely accepted as the cure for menopause. It was not until 1976 that research began to show increased risk of uterine cancer after using hormone therapies. The demand for these hormone drugs began to decline. This forced many companies producing the drugs to look into the research and find acceptable alternatives to the original drug.

From that time until around 2002, hormone replacement therapy was widely accepted. Many women asked for relief from the unpleasant side effects and doctors readily prescribed. It was seen as the choice "cure" for menopausal symptoms and pharmaceutical companies continued making money off of these forms of hormone therapies.

In addition, it was also widely accepted that hormone replacement therapy also could benefit menopausal women by offering added protection against osteoporosis, heart disease, Alzheimer's disease, and degenerative eye diseases. It was not until 2002 that it was shown that hormone replacement therapy could also contribute to a woman's risk for breast cancer. Now doctors are more conservative when prescribing hormone replacement. They often prescribe these hormones in the lowest possible dose and for the shortest about of time.

Now pharmaceutical companies have shown that most women can safely take most forms of hormone replacement therapy. These hormones come in oral pills, gels, and vaginal ring and in the safer, more effective skin patch. Women taking hormone therapy are usually monitored closely by their doctors and have medical check ups every three to six months. Doctors prescribing hormone replacement therapy carefully screen women for uterine cancer and breast cancer before prescribing therapy. Any woman interested in taking hormone therapy should carefully consider the risk as well as the benefits. In addition, women should be aware that taking prescription hormones could be using in conjunction with other methods to lower the risks of cancer.

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